Plenary Talks

Abstract

Will be updated soon

Biography

Dr Sampath Parthasarathy, Ph.D., MBA is an internationally known cardiovascular scientist who holds the UCF College of Medicine�s Florida Hospital Endowed Chair in Cardiovascular Sciences. He is also the Associate Dean for Research. Before joining the college�s Burnett School of Biomedical Sciences November of 2011, Dr. Parthasarathy held the Klassen Chair of Cardiothoracic surgery at Ohio State University. Dr. Parthasarathy is a recognized expert in lipids who is credited with the co-discovery of a major cardiovascular concept � the fact that oxidized LDL is involved in the initiation and progression of atherosclerosis. His areas of interest include atherosclerosis, diabetes, heart failure, Alzheimer�s disease, and cardiovascular nutrition. Dr. Parthasarathy has a breadth of research experience and has published over 250 original articles, including a single author monograph on �Modified Lipoproteins in the Pathogenesis of Atherosclerosis.� He has won several meritorious awards and serves in numerous Editorial Boards. His work is extensively funded by the National Institute of Health (NIH) and AHA and he belongs to an elite group of the most highly cited authors worldwide in his field. He serves on numerous NIH committees.

Speaker
Sampath Parthasarathy / University of Central Florida, USA
Google Scholar H-index 84

Abstract

Biography

His work revolves around improving global health and fostering international partnerships to improve health status of populations. He established the first Community Ophthalmology Department in the public sector in India and headed the department since its inception at Dr. R.P.Centre for Ophthalmic Sciences, AIIMS till he demitted office in 2010. In 2010 established the LSHTM Overseas Centre of Excellence (The South Asia Centre for Disability Inclusive Development & Research) at Hyderabad, India as a collaborative project between LSHTM-PHFI. He worked at WHO, Geneva on the Childhood Blindness Program and was a UNAIDS Consultant with National Aids Control Organization (NACO) for 2 years, where he guided and monitored the first Behavioural Surveillance Survey (BSS) undertaken by NACO and facilitated the development of the first Computerized Monitoring Information System for the National AIDS Control Program. He is an international expert on public health disability and has been engaged in generating evidence on health care access and health concerns of persons with disability and in developing innovative interventions to dismantle these barriers.He has undertaken research projects in India, Bhutan, Bangladesh, Pakistan, Nigeria, Nepal and Sri Lanka. Dr. Murthy is Technical Advisor on Disability to CBM South Asia, Technical Advisor (Research) for Mission for Vision. He is a member of the Queen Elizabeth Diamond Jubilee Trust’s Scientific Advisory Committee, National Task Force on DR and ROP, Optometry Council of India, IAPB DR Technical Advisory Committee. He serves on the editorial board of the Journal for Community Eye Health, Earth Perspectives, Journal of Social Health & Diabetes, Indian Journal of Ophthalmology, Advances in Public Health & Journal of Biomedical Research. He has nearly 300 publications which are indexed in Pubmed.

Speaker
Gudlavalleti V S Murthy / London School of Hygiene & Tropical Medicine
London
UK
H-index: 47

Abstract

Will be updated soon

Biography

Ahdy Helmy, has a MSc and a PhD from Alexandria University, Egypt, then finished a second residency in Internal Medicine, and a fellowship in Endocrinology and Metabolism at Indiana University, USA. He is triple board certified in Medicine, Endocrinology & Lipidology. Is a faculty at Indiana University School of Medicine, USA for the past 20 + years, a distinguished teacher, clinician, an author, and speaker within the USA and abroad.

Speaker
Ahdy W Helmy / Indiana University, USA

Keynote Talks

Abstract

A diabetic with hyper avoidance is like an ostrich with its head in the sand. The chances of a hypoglycemic episode are directly proportionate to how much hyper avoidance is taking place. Hypoglycemia, if not nipped in the bud, can cause clumsiness, confusion, loss of consciousness, seizures, or even death. Hyper avoidance is denial and a psychological reaction; these psychological factors then become a cause of hypoglycemic unawareness. It can manifest because of the patients refusal to accept that diabetes is life threatening or can even be a manifestation of fear and shame of revealing your condition to the people around you or simple omission of self-care because of work related stress. We will be discussing: • Stressful jobs and overworked lives play a major role in people becoming hypo unaware. With so much else to do our own health often takes a back seat. Take the example of a diabetic mother; she has the whole household to take care of, and if she’s a working mother she has office work, house work and the children to consider before she even thinks of herself. These stresses are given priority and cause hypoglycemic unawareness. • A hypoglycemic episode is often very embarrassing. This embarrassment can lead to social awkwardness and a feeling of being ‘other.’ To avoid such fearful revelations from friends and family, and in an effort to not alarm or worry them a diabetic becomes consciously hypo unaware. • Sometimes it isn’t shame, but guilt that makes diabetics hypo unaware. The guilt can stem from feeling somehow responsible for their condition and feelings of hypoglycemia being a punishment they deserve and should handle on their own can have major psychological ramifications. • The fear of not being allowed to do their favorite things also prompts diabetics to avoid mentioning or really being concerned about hypoglycemia. For example a boy who loves swimming will avoid mentioning his medical condition or reporting a hypoglycemic symptom if they think it will ruin their chances of swimming that day. • Sometimes families are not very open about their child having such a condition so the child "learns" about this very early in his diabetes. If he has a hypo in public, he is going to ignore it till the very last minute, in order to be able to hide his condition from people around him because he feels this will embarrass his parents and guilt that he will bring them shame. We will present data, collected through questionnaires, from type 1 diabetic kids and their families during the, “Does Family Influence Hypoglycemia Unawareness” presentation.

Biography

Dr Fauzia Moyeen, has provided training in more than 15 countries in the field of diabetes management and diabetes education. Fauzia loves to educate and has presented at over 300 international, national conferences, workshops and focus groups. Fauzia has a passion for diabetes education and believes education is the corner stone in managing all chronic diseases. In her career as a trainer, she has practiced successfully the theory of empowerment, has vast experience providing training to multicultural audiences, delivered successfully Insulin Pumps and sensors training in Saudi Arabia, UK and Pakistan , and has a keen interest in Type 1 Diabetes in children and the psycho-social aspects of the disease. Conducted numerous workshops for Type 1 diabetic kids and their families.

Speaker
Fauzia Moyeen / CEO of Diabetes Wellness Center
Canada

Abstract

Introduction:Diabetes and its complications were responsible for 8.8% of deaths worldwide in 2017. Many of those deaths could be avoided. Western medicine manages the disease with lifestyle changes and medication. The aim of this study is to demonstrate how in Traditional Chinese Medicine, all diseases are associated with the Yin and Yang imbalances, including diabetes. Although Western medicine and Traditional Chinese medicine (TCM) share the diabetes treatment goals of reducing symptoms and preventing complications, their approaches to conceptualizing, diagnosing, and treating the disease are very different. The methods used in this study were two case reports and bibliographic researches of TCM’s medical literature and Five Elements Theory on the pathophysiology of energy imbalances in diabetes, which lead to the manifestation of the clinical symptoms. The treatment results, looking from the energy point of view, treat the individual as a whole; not only treating the disease but the entire body, as recommends Hippocrates, the father of Medicine. After rebalancing the body’s energy, taking awareness and precaution about internal (emotional) triggers, dietary factors and external (climatic) triggers, the symptoms’ improvement is noticeable. Concluding, when looking at patients as a whole, from the point of view of Yin and Yang energies and Five Elements Theory, we can analyze aspects of the diet normally recommended and the use of hypoglycemic medication and/or insulin, and have a greater balance of hyperglycemic diabetic patients, treating them according to the energy point of view with dietary recommendation, acupuncture, etc.

Biography

Huang Wei Ling, born in Taiwan, raised and graduated in medicine in Brazil, specialist in infectious and parasitic diseases, a General Practitioner and Parenteral and Enteral Medical Nutrition Therapist. Once in charge of the Hospital Infection Control Service of the City of Franca’s General Hospital, she was responsible for the control of all prescribed antimicrobial medication and received an award for the best paper presented at the Brazilian Hospital Infection Control Congress in 1998. Since 1997, she works with the approach and treatment of all diseases of all systems of the human body in a holistic way, with treatment guided through the teachings of Traditional Chinese Medicine and Hippocrates.

Speaker
Huang Wei Ling / Medical Acupuncture and Pain Management Clinic
Brazil

Abstract

Statement of the Problem: Usually, Western Medicine (WM) associates diabetes with a range of complications. According to WM, the longer you have diabetes, higher is the risk of complications. These complications may be disabling or even life-threatening. Some examples are nephropathy, retinopathy, neuropathy, diabetic foot, myocardial infarction, sexual dysfunction and skin issues. According to Traditional Chinese Medicine, the majority of these complications are associated with Yin deficiency and Heat retention. The purpose of this study is to demonstrate that diabetic complications may not be associated with the diabetes, but to the energy alterations responsible for diabetes. They are also causing the diabetes complications. The author based the study in another article entitled “Why are Diabetic Patients Still Having Hyperglicemia, despite Diet Regulation, Hypoglicemic Medication and Insulin?”, In which she explained the energy alteration causing the hyperglycemic condition (Yin deficiency and Heat retention). The energy alterations associated with diabetes are the same energy alterations associated with the complications, as the diabetes and the complications have the same root, Yin deficiency and Heat retention. The conclusion of this study is that to treat what is called diabetic complications presently, it is important to treat the energy imbalances (Yin deficiency and Heat retention), in order to have a greater result in the treatment. When treating only the symptoms, the problem is not treated in the root-level, and neither diabetes nor the complications will be treated properly.

Biography

Huang Wei Ling, born in Taiwan, raised and graduated in medicine in Brazil, specialist in infectious and parasitic diseases, a General Practitioner and Parenteral and Enteral Medical Nutrition Therapist. Once in charge of the Hospital Infection Control Service of the City of Franca’s General Hospital, she was responsible for the control of all prescribed antimicrobial medication and received an award for the best paper presented at the Brazilian Hospital Infection Control Congress in 1998. Since 1997, she works with the approach and treatment of all diseases of all systems of the human body in a holistic way, with treatment guided through the teachings of Traditional Chinese Medicine and Hippocrates.

Speaker
Huang Wei Ling / Medical Acupuncture and Pain Management Clinic
Brazil

Abstract

Diabetes mellitus is an extremely prevalent endocrine disease and a major global public health concern. Diabetic complications, such as retinopathy, nephropathy, neuropathy and cardiovascular disease, are common and majorly impact a patient’s quality of life. Quercetin is an important flavonoid that is ubiquitously present in the diet in a variety of fruits and vegetables. It has been proven that quercetin possesses extensive known pharmacological properties, including anti-inflammatory, antioxidant, and antitumor effects. Increasing evidence suggests that quercetin may offer protection against diabetic complications. The current study focuses on the possible molecular targets and pathways involved in diabetic complications and, in particular, the multi-target approach of quercetin in attenuating diabetic nephropathy, retinopathy, and neuropathy. In diabetic nephropathy, quercetin not only inhibits renal tubular epithelial-mesenchymal transition and renal fibrosis through mTORC1/p70S6K signaling, but also suppresses mesangial cell proliferation through Hippo pathway improving renal function and having protective effect to diabetic nephropathy. Furthermore, quercetin ameliorates diabetic encephalopathy by enhancing a polyfunctional defense enzyme glyoxalase 1 in streptozotocin-induced diabetic rats’ brain. TGF-β2/PI3K/Akt pathway is inhibited by quercetin in diabetic cataract. Despite its proven therapeutic potential, the clinical use of quercetin remains limited because of its low aqueous solubility, bioavailability, and substantial first-pass metabolism. To overcome these challenges, novel formulations of quercetin are developed. The current research prepares biodegradable nanosystems encapsulating quercetin (nano-quercetin) and evaluates the effect of nano-quercetin on diabetic renal dysfunction and fibrosis which expands the clinical application of quercetin.

Biography

Xiaoxing Yin has completed his PhD from Nanjing Medical University of Pharmacology. He is the Vice Director of Jiangsu Province Pharmacological Society, a premier Pharmacological organization. He has published more than 68 papers in reputed journals.

Speaker
Xiaoxing Yin / Xuzhou Medical University
china

Abstract

Diabetes is one of the top leading causes of morbidity and mortality, affecting nearly 600 million people worldwide. Β-cell replacement represents an attractive prospect for diabetes therapy but treatment options remain quite limited .There is increasing hope placed on insulin producing cells derived from human pluripotent stem cells, even as the approach faces continued challenges.The most effective protocols thus far have produced cells that express insulin, and have molecular characteristics that closely resemble genuine insulin-secreting cells. However, these cells demonstrated little sensitivity to glucose as issues that will hopefully resolved in coming years.With the emerging technology in the stem cell science, fetal islet-like clusters (ILCs), obtained from both human and procine pancreatic, have been evaluated for their potential as a source of beta cells. These ILCs contain a large proportion of undifferentiated progenitor cells that only differentiate into fully mature β-cells after transplantation. Another important cell type being explored in mesenchymal stem cells from different human tissues like, bone marrow, umbilical cord, Placenta etc because of their Plasticity “Trans differentiation”. Further, Islet cells can be differentiated from mesenchymal stem cells and differentiated cells can be injected into patients directly. This review summarizes recent progress in obtaining cells that express insulin. My presentation will include introduction about mesenchymal stem cells, their origin and abilities In Diabetes. There will be Discussion of study of stem cell therapy in Type 1 diabetes patients, including role of BCG vaccination in this study group and various informative results.

Biography

Rohit Kapoor, MD(Internal Medicine), Medical Director-Care Well Heart & Super Speciality Hospital, has been practicing more than 25 years in the field of Cardiology & Diabetes. He has 90 research paper presentations in various National & International conferences. He has more than 10 publications in reputed journals. He has been Principal investigator in 35 research studies. He has been invited as speaker faculty in more than 165 conferences and chaired more than 50 conferences. He has been awarded various fellowships like FACC,FACP(USA),FRCP,FISC,FCSI,FDI & FRSSDI. He has contributed 9 chapters in the Textbook of Cardiology & Diabetes. He is pioneer ofr Stem Cell Therapy in Type 1 Diabetes

Speaker
Rohit Kapoor / Care Well Heart & Super Speciality Hospital
India

Sessions:

Session 1

Abstract

Diabetes is considered a “metabolic disease” in that pathophysiology’s associated with diabetes result from deleterious changes in metabolism. Metabolomics is a technique providing a global overview of metabolism that we have applied applied to study the development and progression of diabetic bladder disease (DBD). We have previously reported that diabetes caused both common and differential changes in the bladder detrusor and urothelial layer's metabolome which might explain some of the pathophysiological of the disease. Although insulin reversed most of the metabolic changes, some changes were recalcitrant to glycemic control. This suggests there is potentially “hyperglycemic memory” in the bladder; although hyperglycemic memory is well-documented for other complications of diabetes, such as in retinopathy, nephropathy and macrovascular complications- there are few (if any) reports of this phenomenon associated with DBD. Futher analysis of the metabolic changes caused by diabetes revealed reduced levels of methionine and betaine, which would result in a “methyl-donor substrate” deficiency, potentially leading to modulated methylation of genomic DNA. Therefore, we analyzed changes in the methylation pattern of gDNA isolated from bladder, and confirmed that diabetes causes changes in the methylation of specific genes, which are reversed by insulin in most, but not all, of these genes. The genes that did not have normalization of methylation patterns following insulin treatment were involved in the metabolic pathways identified as not reversed by insulin. Thus, our studies on DBD combining metabolomic and epigenomic studies have provided not only insights into its development, but also evidence for hyperglycemic memory in DBD.

Biography

Dr. Kelvin P Davies is Professor of Urology, Physiology and Biophysics at Albert Einstein College of Medince in the USA. A major focus of his research has been on identifying the underlying mechanisms by which diabetes results in urological disease. He has over 50-peer reviewed publications, is currently supported by grants from the National Institute of Diabetes and Digestive and Kidney Diseases of the NIH and serves on the Steering Committee of the Diabetic Complication Consortium (diacomp.org).

Speaker
Kelvin P. Davies / Albert Einstein College of Medince
USA

Abstract

Statement of the Problem: Gestational Diabetes (GD) is high-blood sugar that develops during pregnancy and usually disappears after giving birth. In Traditional Chinese Medicine (TCM), the physiopathology of GD is Yin deficiency and Heat retention. Purpose: To demonstrate the importance of chakras and energy imbalances measurement in the prevention and treatment of pregnant patients, and also in pregnant patients with diagnosis of GD. Methodology: Two case reports. The first, a 33-year-old female patient, first pregnancy, pregnant of twins, diagnosed with GD in the 21ª week of pregnancy. Was diagnosed after evaluation of the babies size (above percentile 85). Glucose tolerance test resulted 81; 231; 187 mg/dl. She was oriented to reduce carbs, sweets and some fruits. Had a previous chakras energy measurement evaluation, two years before the pregnancy, and had weakened energy, due to stress. The medication for the chakras was recommended by a year, and she only took it during one month. In the second patient’s case, her glucose tolerance test appeared 156 mg/dl (normal 140 mg/dl). Both patients’ chakras were at the level 1 of 8, with significant lack of energy. Results: Both patients with GD had deficiencies of the energy of the chakras. Conclusion & Significance: To prevent and treat GD, it is important to correct the chakras and other energy imbalances that are leading to Yin deficiency with Heat retention, the root of the problem, according to TCM.

Biography

Huang Wei Ling, born in Taiwan, raised and graduated in medicine in Brazil, specialist in infectious and parasitic diseases, a General Practitioner and Parenteral and Enteral Medical Nutrition Therapist. Once in charge of the Hospital Infection Control Service of the City of Franca’s General Hospital, she was responsible for the control of all prescribed antimicrobial medication and received an award for the best paper presented at the Brazilian Hospital Infection Control Congress in 1998. Since 1997, she works with the approach and treatment of all diseases of all systems of the human body in a holistic way, with treatment guided through the teachings of Traditional Chinese Medicine and Hippocrates.

Speaker
Huang Wei Ling / Medical Acupuncture and Pain Management Clinic
Brazil

Abstract

Background: NAFLD is a disease characterized by increased hepatic fat with a global prevalence of 25.2%. NASH, a subtype of NAFLD is characterized as having varying degrees of fibrosis, hepatic fat, hepatocyte injury, and inflammation. Both forms of NAFLD can progress to cirrhosis and hepatocellular carcinoma with this progression occurring more frequently with NASH. The health care costs of NAFLD are substantial as a result of the number of hospital admissions, the severity of the underlying liver disease, hepatic and non-liver disease mortality, all of which are greater in NASH as compared to NAFLD. Thus, it is important to distinguish between NAFLD and NASH. A host of algorithms have been used for this purpose with only modest success. Ultrasound assessments using transient or shear wave (SWE) have been used for this purpose with the latter having the advantage of estimating the hepatic fat content determined by the determined hepatorenal ratio (HRR). More recently, MRE has been utilized as well. SWE is more available, cheaper, and less demanding in terms of time commitment and experience as compared to MRE which is limited to a few research centers. AIM: To identify a serologic marker that distinguishes those with NASH from those with NAFLD. Methods: From a total of 105 patients investigated with SWE, 40 patients were selected after matching for BMI, presence of type 2 diabetes mellitus, hypertension, and hyperlipidemia. 10 were identified as liver disease controls not having NAFLD, and 15 with NAFLD and 15 with NASH. Each individual had the following studies performed: Complete blood count, BUN, creatinine, prothrombin time, aPTT, total bilirubin, AST, ALT, alkaline phosphatase, gamma glutamyltranspeptidase, blood sugar, hemoglobin A1c, plasma leptin and adiponectin. ANOVA utilizing the EPI 7 program of the CDC was utilized for the statistical analyses Results: The only laboratory parameter that distinguished those with NASH from those with NAFLD and the liver disease controls was the plasma level of leptin (P < 0.03). Adiponectin levels declined progressively as the measures of glucose dysregulation(fasting blood sugar and insulin levels) increased (P < 0.05). Conclusions: The plasma level of leptin was the only factor that distinguished individuals with NASH from those with either NAFLD without NASH and the liver disease controls.

Biography

Dr. Van Thiel graduated from the UCLA, completed his education at Cornell University hospitals, the NIH, Boston Univ.,and the Univ. of Pittsburgh. He served as the president of the AASLD , RSA, and Midwest AFCR. He has 1100 publications. He was awarded the Albert Nelson Marquis lifetime achievement award in 2017

Speaker
David Van Thiel / Advanced Liver and Gastrointestinal Disease Center
USA

Abstract

Adhesive capsulitis (AC) of shoulder is a common medical condition which occurs in 2-5 % of the population.Incidence of AC is reported to be five times higher in patients with Diabetes. Aim: To study the correlation between the levels of HbA1c and the disability improvement. following physical therapy in patients with AC. Methodology: A prospective interventional study on patients referred to physiotherapy with adhesive capsulitis was conducted. Outcome measures were analyzed using Shoulder Pain & Disability Index. All patients enrolled into the study are tested for HbA1c and followed by Physical Therapy interventions.Outcomes of physiotherapy intervention on SPADI score and improvement in Range of motion were collected and analyzed .Results: 62% of patients referred for physiotherapy with adhesive capsulitis had diabetes, with a mean Hba1c of 7.8 %, 23% had pre-diabetes and 15 % had a Hba1c of <5.7%. The mean SPADI prior to intervention was 69 % in the whole group which improved to 46% post physiotherapy. Patients with Diabetes had a mean SPADI score of 61 % on initial evaluation and improved to 54% upon discharge. SPADI score had significant improvement in the Non diabetic group compared to the Diabetic group.Outcomes: Results from initial observation showed a high incidence of diabetes among patients referred with adhesive capsulitis. Two patients were diagnosed as Diabetic post referral for Physiotherapy. In the patient cohort, the Diabetic group had greater disability, pain and decreased rate of improvement in Range of motion of the shoulder joint compared to the Non diabetic group.

Biography

Mr.Roy Mathew has completed his Masters Degree in Physiotherapy from India and acquired Certified Manual Therapy from Manual Concepts,Australia. He is currently working as a Physical Therapy Specialist with Hamad Medical Corporation Doha,Qatar since 2006.He also posses a Certified practitioner in Mechanical Diagnosis and Therapy,McKenzie Institute,NewZealand.

Speaker
Roy Mathew / Hamad Medical Corporation
Qatar

Abstract

Objective: The objective of this review is to assess the efficacy of yoga on type 2 diabetes (T2DM) management. Design: Systematic review and meta-analysis of randomized clinical trials (RCTs) comparing the practice of any type of yoga, asanas or pranayamas vs. standard care in adults with T2DM. Outcome measure is selected as positive change in the glycemic control either fasting plasma glucose or HbA1c. Secondary outcomes identified included lipid profile, and psychological parameters. Data Source: The electronic databases such as PubMed, Cochrane, Scopus, Medline, Embase and CINAHL were searched from the year 1990 to August 2015 to find out the studies done on yoga as per the eligibility criteria. Results: 9 RCTs were found to be eligible as per the inclusion criteria involving 788 participants. Of the 9 studies, 3 studies found that yoga has significantly reduced HbA1c. 2 studies reported the significant effect of yoga on psychological, social domains and total quality of life. Meta-analysis of 5 studies using fixed effect showed a mean difference in HbA1c between yoga and control as -0.51% (95 % CI -0.57 to -0.44) with P =0.006. Meta-analysis of 5 studies and subgroups using fixed effect showed mean difference in fasting plasma glucose (mg/dl) between yoga and control as -25.23 (95 % CI -25.31 to -25.16) with P <0.00001 for the yoga intervention on fasting plasma glucose. Conclusion: The results suggest that yoga can be a promising intervention for the treatment of T2DM as an adjuvant therapy.

Biography

Speaker
Rashmi Shiju / Dasman Diabetes Institute
Kuwait

Abstract

As well-known, Non-invasive Glucose Monitoring(NGM) technology is promising and desired for patients andpeople with high-risk hyperglycemia or hypoglycemia. In variouskinds of NGM technologies, a prediction algorithm model playsa special role that is to map a group of physical signals to aglucose level of a person at a given time. Unfortunately, there isno a practical solution available to public, under circumstances ofdifferent ages, gender, living styles, physiological differences, etc. In this talk, “A Self-Learning Prediction Model for NoninvasiveBlood Glucose Monitoring” is proposed, called Artificial NeuralNetwork with a Transfer and Collaborative Learning method(ANN-TCL), in which blood glucose model parameters of anindividual can be tuned to his/her own health conditions viatransfer and collaborative learning methods. To verify performanceof the proposal, it is embedded into our developed NGMsystem, and compared with alternate solutions. Clinical trials inthe PLA NAVY General Hospital demonstrate that this proposalcan achieve expected results for all test subjects with a fastmodel training. Obviously, it is helpful to each patient with our NGM system for the purpose of glucose self-monitoring andhealth-risk self-management. Furthermore, the proposal with thecombination of LSTM can serve the continuous NGM purposewith the expected precision. Based on our best knowledge, it isthe first prediction model that the mean of squared correlationcoefficient (R2) can reach 0.82, which is good enough for patient’sblood glucose self-management (since R2 0.85 value is an ISO gold standard for all kinds of glucometers used for clinical diagnosis). The unique gain is benefit from a special design in thismodel, in which a self-learning strategy can fully take advantageof both universal and personal information. Please note, thismodel can be extended to other glucometers.

Biography

Dr. Anpeng Huang is the assistant dean of national institute of health data science, and an Associate Professor of Peking University, Beijing, China. From 2015, he serves as the chief scientist of national Health Big-Data and Health IT Science and Technology program. He has more than 70 journals and conference papers, is the holder of 36 patents and US patents (with PCT application), the advisor of "Best Student Paper Award" winner at 2012 14th IEEE HEALTHCOM conference, and the founder of mobile health lab in PKU. His research interest includes health big-data, mobile health, AI for smart health, etc.

Speaker
Anpeng Huang / National Institute of Health Data Science, Peking University, Beijing, China.

Abstract

Diabetes is commonly perceived to comprise two distinct processes commonly referred to as type 1 and type 2 diabetes. Each is considered to be a distinct process however difficulties continue to exist concerning the ability of current tests to diagnose diabetes with the result that patients may be misprescribed medication or may not need medication or would benefit from other interventions. The author illustrates that type 1 and type 2 diabetes exist as coexistential morbidities in which the type 1 condition is associated with the ability of a spectrum of genes to act coherently and express the insulin precursor pre-pro-insulin (genotype) and the type 2 condition is associated with the ability of insulin to react with its receptor protein (phenotype). Yet this does not entirely explain the phenomena of diabetes in which the brain regulates levels of blood glucose between upper and lower limits of typically 4-8mmol/l; or how pathologies in other organs and/or systems can influence blood glucose levels; or how changes of colour perception accompany pathological onset. So what is missing from current etiology? If there are changes of molecular biology (i.e. pathological onset) this must influence cell biology, organ function, and the coherent function of the organ networks (physiological systems). Moreover the GP's consultation remains based upon a rudimentary and imprecise understanding of these physiological systems. So what are these physiological systems and why are they important? The function of the brain is to continuously monitor and optimise the body's physiological stability i.e. to maintain physiological parameters between upper and lower limits. Each of these neurally regulated systems performs a distinct physiological function. In the regulation of blood glucose the most significant of these systems appear to be the optimisation of pH, sleep, and sexual function. Pathological onset and/or instability in these organ systems leads to multi-pathological and/or multi-symptomatic onset in other organs and organ systems e.g. leading to diabetes, hypertension, chronic kidney disease, circulatory problems, depression, Alzheimer's disease, etc. So how can we measure such a complex phenomena in which pathological onset occurs across a spectrum of systems and organs? Changes of colour perception accompany the onset of diabetes as a result of the emission of biophotons as proteins decay to their unreactive state following pathological reactions resulting from stress, hyperindulgence, the consumption of acidified and/or alcoholic beverages, etc. Many companies have sought, invariably unsuccessfully, to adapt this phenomena perhaps because they have sought to make a simplistic association between changes of colour perception and diabetes rather than considering the complex nature of the association(s). The Human Brain Project was established to understand what the brain does and how it does it - it functions as a neuromodulator which continuously optimises the body's physiological stability; to use such knowledge to develop a new generation of cognitive diagnostic with particular emphasis upon the diagnosis of complex medical conditions such as Alzheimer's Disease; and to understand and adapt with therapeutic effect the multilevel nature of brain function. Such knowledge - for example as the Strannik Virtual Scanning test - has the capability to be able to screen the patient more effectively i.e. in far greater levels of precision and sophistication, than current tests; to establish the onset of diabetes and diabetic comorbidities; and at lower cost, perhaps significantly so. Moreover, the understanding of the relationship between sense perception, brain function, the autonomic nervous system and physiological systems, and pathological onset; has significant therapeutic potential.

Biography

Speaker
Graham Wilfred Ewing / Mimex Montague Healthcare
United Kingdom

Abstract

Diabetes is a major chronic ailment that extensively impacts the global population. It is a global epidemic and the most expensive disease. Diabetes mellitus refers collectively to a group of diseases resulting from dysfunction of the glucoregulatory system, Hyperglycemia, the hallmark of diabetes, is the primary consequence of this dysregulation. Chronic hyperglycemia in diabetes is associated with long-term complications involving tissue damage and organ failure, which can decrease life expectancy and even cause death. Artificial intelligence (AI) methods in combination with the latest technologies, including medical devices, mobile computing, and sensor technologies, have the potential to enable the creation and delivery of better management services to deal with chronic diseases. One of the most lethal and prevalent chronic diseases is diabetes mellitus, which is characterized by dysfunction of glucose homeostasis. Several studies have been published on the application of AI to diabetes in a broad range of management domains. The potential of AI to boost effective and accurate management of diabetes has been demonstrated in many areas. Research in this field should focus on opportunities and advantages of applying AI methodologies in diabetes management that differentiate these strategies from the classical approaches.

Biography

Dr Ellahham is currently Cleveland Clinic Caregiver, Cleveland,US seconded as Senior Cardiovascular Consultant and Quality Advisor in Cleveland Clinic Abu Dhabi. Dr. Ellahham received his undergraduate degree in biology and his M.D. from the American University of Beirut, Beirut, Lebanon. Dr Ellahham finished his internal medicine residency in Georgetown University Hospital - Washington Hospital Center and his fellowship in Cardiology at the Virginia Commonwealth University Health System in USA.

Speaker
Samer Ellahham / Cleveland Clinic caregiver
USA

Abstract

It has been recently shown that nutritional ketosis is effective against seizure disorders and various acute/chronic neurological disorders. Physiologically, glucose is the primary metabolic fuel for cells. However, many neurodegenerative disorders have been associated with impaired glucose transport/metabolism and with mitochondrial dysfunction, such as Alzheimer’s/Parkinson’s disease, general seizure disorders, and traumatic brain injury. Ketone bodies and tricarboxylic acid cycle intermediates represent alternative fuels for the brain and can bypass the rate- limiting steps associated with impaired neuronal glucose metabolism. Therefore, therapeutic ketosis can be considered as a metabolic therapy by providing alternative energy substrates. It has been estimated that the brain derives over 60% of its total energy from ketones when glucose availability is limited. In fact, after prolonged periods of fasting or ketogenic diet (KD), the body utilizes energy obtained from free fatty acids (FFAs) released from adipose tissue. Because the brain is unable to derive significant energy from FFAs, hepatic ketogenesis converts FFAs into ketone bodies-hydroxybutyrate (BHB) and acetoacetate (AcAc)-while a percentage of AcAc spontaneously decarboxylates to acetone. Large quantities of ketone bodies accumulate in the blood through this mechanism. This represents a state of normal physiological ketosis and can be therapeutic. Ketone bodies are transported across the blood-brain barrier by monocarboxylic acid transporters to fuel brain function. Starvation or nutritional ketosis is an essential survival mechanism that ensures metabolic flexibility during prolonged fasting or lack of carbohydrate ingestion. Therapeutic ketosis leads to metabolic adaptations that may improve brain metabolism, restore mitochondrial ATP production, decrease reactive oxygen species production, reduce inflammation, and increase neurotrophic factors’ function. It has been shown that KD mimics the effects of fasting and the lack of glucose/insulin signaling, promoting a metabolic shift towards fatty acid utilization. In this work, the author reports a number of successful case reports treated through metabolic ketosis.

Biography

Raffaele Pilla, Pharm.D., Ph.D., Doctor Europaeus, received his Master’s degree in Pharmacy at G. d’Annunzio University in Chieti-Pescara, Italy in 2005, where he also served internships at the Cell Physiology Laboratory and Molecular Biology Laboratory. Prior, he was an Erasmus Student at Faculté de Pharmacie de Reims in Reims, France. He received his Doctor Europaeus in 2010 from Pitié-Salpétrière Institute in Paris, France. Also in 2010, he received his Ph.D. in Biochemistry, Physiology, and Pathology of Muscle at G. d’Annunzio University in Chieti-Pescara, Italy. He was hired as a Postdoctoral Scholar in the Department of Pharmacology and Physiology at the University of South Florida in Tampa, on two research grants funded by the Office of Naval Research (US Navy) and Divers’ Alert Network. He has written and lectured widely worldwide. He has been involved in ongoing research at the University of South Florida with the use of ketone esters.

Speaker
Raffaele Pilla / St. John of God Hospital
Italy

Abstract

Endocrine diseases are characterized by hormonal alterations (excess or defect). Due to the low prevalence (less than five case 5 / 10 000 inhabitants), a large number of them, qualify to be classified as rare diseases such as those of organs like: hypophysis, adrenal glands, gonads as well as some congenital thyroid diseases. Others like Diabetes are considering almost epidemic. The objective of this study is to define the types of diseases observed in the only Endocrinology Clinic in Guyana. The diagnoses of all patients who attended the endocrinology clinic of the Georgetown Public Hospital Corporation from June 1, 2016 to May 31, 2017, were analyzed. During the one year of this study, approximately 639 patients attended the endocrinology clinic. Of this, 178 patients had thyroid-related diseases with 80 of these having thyrotoxicosis, 49 having hypothyroidism followed by 110 patients with diabetes mellitus. Pituitary tumors were also diagnosed with 2 of acromegaly and 6 of prolactinomas. Cases of hypoadrenalism (n = 5), hypogonadism (n = 4),) and pheochromocytoma (n = 6) were not rare; gonadal disease were also found in 17 patients. Thyroid disease was the most frequent diagnosis followed by diabetes mellitus. New emerging endocrine disorders such as hyperlipidemia (n = 1) were rare. Some persons attending the clinic were also noted to be overweight /obese however this was not the primary reason for joining the clinic. Traditional diseases such as Sheehan Syndrome have become rare due to improvements in Obstetric care.

Biography

Yaquelin. Ricardo has completed his MD program in 1995, the First and Second Degree (2001) in Endocrinology from Higher Institute of Medical Sciences, Cuba and 2 MsC studies from Medical Sciences University of Havana , Cuba. She is the Endocrinologist consultant of Georgetown Public Hospital Corporation , the main teaching and research hospital in Guyana and Adjunct Assistant Professor Universidad Guyana .She has published more than 12 papers in reputed journals and the Cuban national medication form. She has been serving as an editorial board member of repute.

Speaker
Yaquelin. Ricardo / Georgetown Public Hospital Corporation
Guyana

Abstract

Deep learning is evolving in the areas such as gene regulation, genome organization, and mutation effects. It helps in detecting introgression, estimating historical recombination rates, identifying selective sweeps and estimating demography of population genetics. Deep Learning based genome models have mRNA alignments, DNA mapped repeat elements, gene predictions, gene-expression data and data related to a disease. Disease related represents the relationships of genes to diseases. Expression tracks provide correlation of genetic data with the tissue areas. They help in identifying the linkage of a gene with body tissues. Diabetes can be categorized into Type1, Type2, Gestational, LADA,MODY and double types. Type1 diabetes is developed due to variants of HLA-DQA1, HLA-DQB1, and HLA-DRB1 genes. HLA-DQA1, HLA-DQB1, and HLA-DRB1 genes help in creating proteins which help in the human body immunity. Type 2 diabetes are due to TCF7L2, SLC30A8, HHEX, FTO, PPARG, and KCNJ11 gene variants. Deep learning method can used for diabetes specific biological datasets which will be in the order of thousands. The black boxed deep neural networks can be used to learn from the data sets regarding the gene variants and to create a genome model. Small variations help in identifying patterns for creating genome models. The size of the input data helps in improving the accuracy of the model. Deep variant method helps in identifying small mutations in the genome data. Biologic pathways apart from DNA sequence predict the diabetes disease association with genome model.

Biography

Bhagvan Kommadi is the Founder of Architect Corner - AI startup and has around 19 years’ experience in the industry, ranging from large scale enterprise development to helping incubate software product start-ups. He has done Masters in Industrial Systems Engineering at Georgia Institute of Technology (1997) and Bachelors in Aerospace Engineering from Indian Institute of Technology, Madras (1993). He is member of IFX forum,Oracle JCP and participant in Java Community Process. Bhagvan Kommadi founded Quantica Computacao, the first quantum computing startup in India. Markets and Markets have positioned Quantica Computacao in ‘Emerging Companies’ section of Quantum Computing quadrants. Bhagvan has engineered and developed simulators and tools in the area of quantum technology using IBM Q, Microsoft Q#, and Google QScript. Company's focus is on developing quantum cryptographic tools which will be able to provide quantum proof data security, which will help the banking institution to protect their transactions.

Speaker
Bhagvan Kommadi / Quantica Computacao
India

Abstract

The burden of diabetes mellitus is constantly increasing demographically and financially. Prediabetes on the other hand is often left undiagnosed. This eventually progresses to diabetes mellitus increasing the mortality and morbidity. Research on Prediabetes and its prevention is limited and less widely used. Complications which can happen in due course of Diabetes mellitus sometime begin during Prediabetes which makes this a potential area of target in modern era with wide resource availability. Serum insulin, glucose levels, HbA1c, measuring insulin resistance and clinical judgement play a vital role in the management of Prediabetes. There is a possibly another classification of Diabetes staging which includes subclinical Diabetes. Hence proper emphasis on various strategies to detect subclinical and pre-diabetes in its early stage and reversal is the need of the hour.

Biography

Dr. Waseem Ahmed N is a Family physician subspecialised in diabetes management and geriatrics. He has more than 5 years of rich experience in the field of Diabetes with various presentations in national and international forums. He is one among the youngest researcher in the field of Diabetes in the country and an active YouTuber.

Speaker
Waseem Ahmed / CRAFT Hospital and Research Centre-Kerala
India

Abstract

The problem of therapeutic non-adherence is a serious issue adversely affecting the adequate control and management of Type2 Diabetes (T2D).This unwelcoming situation has been studied well on various spots on the globe, with diverse results. The present study, aimed at identifying the barriers to therapeutic adherence, was conducted on a set of proven cases of T2D, managed by primary healthcare providers. The adherence rate to medication alone was 42% while to medication plus lifestyle recommendations 27%. Whereas sub-optimal health literacy, complexity of prescription and socioeconomic aspects were the main determinants, lapse on the part of healthcare system cannot be underscored. The present qualitative study was a preliminary investigation on a small sample .The magnitude of the problem necessitates that a large scale multi-centre in-depth quantitative study in 5 dimensions (recommended by WHO): socio-economic factors, health care team and system related factors, condition related factors , therapy related factors and patient related factors, be done on priority basis. This would pave the way for planning a well-designed intervention programme.

Biography

Dr. Mujtaba has completed his fellowship in Internal Medicine from College of Physicians and Surgeons of Pakistan. He is a member of Royal College of Physicians and Surgeons, Glasgow, UK and a fellow of American College of Chest Physicians. He has over 23 years of experience in the field of Internal Medicine and has many research papers published in international and national journals. Currently, he is working as Consultant Physician/Endocrinologist and Asst. Professor of Medicine at Akhtar Saeed Medical and College, Lahore.

Speaker
Mujtaba Hasan Siddiqui / Akhtar Saeed Medical and College
Lahore

Plenary Talks

Abstract

Will be updated soon

Biography

Sergey Suchkov graduated from Astrakhan State Medical University and awarded with MD, In 1985 he completed his Ph.D. at I M Sechenov Moscow Medical Academy and in 2001, maintained his Doctorship Degree at the Nat Inst of Immunology, Russia. From 1987 through 1989, he was a senior Researcher, Koltzov Inst of Developmental Biology. From 1989 through 1995, he was a Head of the Lab of Clinical Immunology, Helmholtz Eye Research Institute in Moscow. From 1995 through 2004, he was a Chair of the Dept. for Clinical Immunology, Moscow Clinical Research Institute. He has been trained at: NIH; Wills Eye Hospital, PA, USA; Univ. of Florida in Gainesville; UCSF, S-F, CA, USA; Johns Hopkins University, Baltimore, MD, USA. He was an Exe Secretary-in-Chief of the Editorial Board, Biomedical Science, an international journal published jointly by the USSR Academy of Sci-ences and the Royal Society of Chemistry, UK. At present, he is a Chair, Dept. for Personalized and Translational Medicine, I M Sechenov First Moscow State Medical University. He is a member of the New York Academy of Sciences, USA; American Chemical Society (ACS), USA; American Heart Association (AHA), USA; EPMA (European Association for Predictive, Preventive and Personalized Medicine), Brussels, EU; ARVO (American Association for Research in Vision and Ophthalmology); ISER (International Society for Eye Re-search); PMC (Personalized Medicine Coalition), Washington, USA.

Speaker
Sergey V. Suchkov / I M Sechenov First Moscow State Medical University
Russia

Abstract

Will be updated soon

Biography

Zeev Blumenfeld is MD for Hebrew University and Hadassah Medical School, Jerusalem, and he is the Director for Reproductive Endocrinology for the department Obstetrics & Gynecology. He worked as Director in the year 2010 for Reproductive Endocrinology; he is a Senior Physician for Reproductive Endocrinology and Infertility, OB/GYN. He has an extensive and vast teaching experience in the field of "Reproductive Endocrinology". He taught Director of Endocrinology Course for medical & graduate students, Director of �Physiology of Reproduction� course. He worked as a Reviewer for many scientific Journals. He also has membership for International and National professional societies. He Elected as member of the "Society for Gynecologic Investigation". Worked as Editor in Chief- �Clinical Medicine Insight: Reproductive Health�, "Journal of Reproductive Biology and Health". Zeev Blumenfeld advanced studies: 1983-1985 Fellowship in Reproductive Endocrinology in the Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, 1993- Exon-Intron Workshop on Molecular Biology - Recombinant DNA Methodology, 1993. 2014- Completed the program of GCP & clinical trials management for PI's. He had 27 Publications.

Speaker
Zeev Blumenfeld / The Hebrew University of Jerusalem
Israel

Sessions:

Session 2

Abstract

Buckwheat sugar shows anti-diabetic activity and a potential pre-biotic activity (1) Buckwheat, also known as common buckwheat, Japanese buckwheat (2) has a botanical name of Fagopyrumesculatum. It decreases the blood glucose levels. The name 'buckwheat' or 'beech wheat' comes from its triangular seeds, which resemble the much larger seeds of the beech nut from the beech tree, and the fact that it is used like wheat (3) Buckwheat (FagopyrumesculentumMoench) is an alternative crop belonging to the Polygonaceae family. In comparison to antioxidant activity of frequently used cereals, buckwheat has been reported to possess higher antioxidant activity (AOA) (4) A 68 years old male, known case of Hypertension and Diabetes, married having children, on vegetative mixed diet and family history negative for CAD, presented with complaints of left sided chest pain and SOB. No history of Syncope. Was admitted in Star hospital,8-2-596/5, Road no 10,Banjara hills, Hyderabad, Telangana State,India on August 9, 2017,with IP No- IP1708008061.Diagnosed as CAD-Triple Vessel disease. Good LV Function. He was operated on August14, 2017, CABG X 3 GRAFTS on beating heart. The patient was discharged on August 21, 2017.Currently the patient is using DEPLATT,ECOSPORIN, ANGISPAN AND RANOZEX. The patient is not using any antidiabetic drugs. On admission, i.e., August 9, 2017, random plasma glucose was 344 mg/dL and HbA1c 9.0%. The patient has been consuming cooked Buckwheat with vegetables along with bread (Roti) every day in lunch and dinner. The blood sugar levels were recorded. Random plasma glucose is oscillating between 80 -145mg/dL. HbA1c reduced to 7.2%

Biography

M V Raghavendra Rao, PhD, worked as Professor of microbiology, parasitology, immunology and epidemiology in many universities in India, China, Nepal, Libya, and Philippines. Currently, he is working at Avalon University School of Medicine, Curacao, Netherland Antilles. He has more than 40 years of teaching and research experience. He supervised 3 students for PhD, and 8 students for MPhil. He authored 18 text books. Three universities appointed him as their advisor and 3 universities acknowledged him with fellowships.

Speaker
M.V.Raghavendra Rao / Avalon University School of Medicine
Netherlands Antilles

Abstract

Interleukin (IL)-33 is constitutively expressed in the nucleus of various cell types including pre-adipocytes, adipocytes, and endothelial cells; and can also be secreted as a cytokine upon activation of some immune cells. The receptor for the cytokine IL-33 is ‘suppression of tumorigenicity 2’ (ST2), which can either be expressed on the cell surface (ST2L) or secreted as a soluble protein (soluble ST2, sST2). Membrane-bound ST2L confers the biological functions of IL-33, while sST2 serves as an antagonistic decoy receptor. The IL-33/ST2 axis is protective against obesity, insulin resistance, and type 2 diabetes (T2D) in animal models. We recently showed that adipose tissue IL-33 is inversely correlated with glycated hemoglobin (HbA1c) in individuals with normal glycemia but not in those with prediabetes. This inverse correlation was also observed in individuals with T2D, and additionally, IL-33 was inversely correlated with fasting plasma glucose in those who had better glycemic control. Importantly, adipose tissue IL-33 was directly correlated with its receptor ST2 in individuals with normal glycemia and T2D but not prediabetes. In addition, adipose tissue IL-33 (as well as ST2) showed different correlation patterns with other immunometabolic biomarkers in the adipose tissue of individuals with normal glycemia, prediabetes and T2D. These findings suggest that IL-33 and/or IL-33/ST2 dynamics and biological functions may play a role in overall glycemia among humans and may represent a novel target by which glucose-lowering agents confer their beneficial effects.

Biography

Amal Hasan is a scientist in the Department of Immunology and Microbiology at Dasman Diabetes Institute, Kuwait. She was awarded an MSc in Immunology and Allergy, and a PhD in Immunology from the University of Nottingham, United Kingdom. Dr. Hasan worked as a Medical Laboratory Practitioner in the Department of Immunology at Hamed Al-Essa Organ Transplant Centre, before assuming a research position at Dasman Diabetes Institute. She has published 11 peer-reviewed articles, 1 book chapter, and has two patent applications. Dr. Hasan has also been serving as an invited reviewer in reputable journals and is a member of the British Society for Immunology, and the American Diabetes Association.

Speaker
Amal Hasan / Dasman Diabetes Institute, Kuwait

Abstract

Background: Diabetes Mellitus (DM) is a growing epidemic metabolic syndrome, which currently affects near 5.6 % of people worldwide. In addition, regardingthe economic aspect, approximately 12% of health expenditure is dedicated to this disorder. Due to long-lasting asymptomatic clinical manifestation, discovery and developing biomarkers as a practical guideline with high specificity and sensitivity for the diagnosis, prognosis and clinical management of DM is one of the subjects of great interest among DM researchers. In this study we described recently identified molecular biomarker involved in DM. Method:Eligible studies were searched at diabetes research center, ShahidSadoughi University of medical sciences in PubMed, Scopus, Google Scholar and web of Science by considering the keywords such as “diabetes mellitus”, “biomarker”, “microRNA”, “diagnostic tool” and “clinical manifestation”. Result:A total of 107 studies were finally included in our review. After evaluating numerous articles including original, meta-analysis and review we focus on molecular biomarker that are involved in diagnosing and management of DM. Conclusion:increasing interest in biomarkers relating to DM, goes back to its role in decreasing diabetes-related morbidity and mortality. This review emphasizeson major molecular biomarkers including proteomic and microRNA (miRNAs) as a novel and interesting DM biomarkers. Thus, these biomarkers help us to achieve timely diagnosis of DM.

Biography

Mohammad Yahya Vahidi Mehrjardi has completed his PhD in molecular genetics at the age of 29 years from Science and Research Branch Islamic Azad University. He is the Head of Genetics Unit, Yazd Diabetes Research Center and Manager of the Medical Genetics Research Center ShahidSadoughi University of Medical Sciences. He has published more than 30 papers in reputed journals and he has written 3 books about diabetes and genetic factors.He has been awarded a science prizeof 7thYazd International Student Award in Reproductive Medicine.

Speaker
Mohammad Yahya Vahidi Mehrjardi / ShahidSadoughi University of Medical Sciences
yazd
Iran

Abstract

Background: Pregnancy tends to reset the glucose homeostasis in the direction of diabetes. About 1-2% of all pregnant women develop an abnormal glucose tolerance in pregnancy, but most often glucose tolerance returns to normal postpartum. This condition is called gestational diabetes mellitus (GDM). Objective: Comparative study between gestational and pregestational diabetes (PGDM) in relation to glycemic control as regarding neonatal outcome. Methods: This study was conducted in Kasralainy Maternity hospital in Egypt from september 2017 to march 2019 and it included 120 pregnant women complicated by DM attending outpatient clinic or inpatient. Patients were classified into two groups, Gestational Diabetes: 60 pregnant women complicated by DM which is diagnosed for the first time during pregnancy and Pregestational Diabetes: 60 pregnant women who have DM that has been diagnosed prior to pregnancy. The two groups were compared according to neonatal complications. All patients were 18 to 40 years old, singltone pregnancy,and with time of termination after completed 37 weeks. Result: Neonatal complications, such as respiratory distress syndrome (RDS), neonatal hypoglycaemia, neonatal jaundice and subsequent admission to a neonatal intensive care unit (NICU) were significantly higher for neonates born to mothers with PGDM compared to those born to mothers with GDM (P 0.001). Conclusion: women with PGDM were at higher risk of developing neonatal complications. Glycemic control started as early as possible (the best being preconceptional) is important to decrease the incidence of these complications.

Biography

Will update soon

Speaker
Mohamed Hussein / Cairo University
Cairo
Egypt

Will be updated soon...