Prof. Yu-long Yin has completed his PhD from Queen's University Belfast, KU and visiting researcher in Max Planck institute, Germany. He is the director of Animal husbandry farming center, Institute of Subtropical and Agriculture, China Academy of Sciences, and vice chairman of Hunan Science Association, China. He has published more than 350 papers in reputed journals and has been serving as a Chief Editor of Animal Nutrition, and an editorial board member of Journal of Animal Science.
Seohyun Park has studied Korean Medicine from Dongguk University, Korea, and she has been taking doctoral course at same university. She is working as a fellow of medical department, rehabilitation of Korean Medicine, in Bundang Oriental Hospital of Dongguk University. She has been studied the disorders which is related to spinal disorders.
DrAlicja Bauer is a senior lecturer at the Centre of Postgraduate Medical Education in Poland. She give a lecture for physiciansand laboratory workers. She is the scientific director of specialist and practical courses of autoimmune diseases, chronic liver and intestinal diseases. She has been interested in the diagnosis of primary biliary cholangitis (PBC) and cooperate with the Clinic of Gastroenterology and Hepatology, working in the project “Primary biliary cirrhosis (PBC) in Poland – clinical characteristics, analysis of relationships between genetic and molecular variants and disease phenotypes”, which could determine the helpful prognostic factors in PBC.
Presently working as Associate Professor at Avalon University School Of Medicine, Willemstad, Netherlands Antilles.
Graduated from Yerevan State Medical University, Armenia. Post-Graduation in Anatomic & Clinical Pathology at Dr NTR University of Medical Sciences (Masters Pathology & Diploma in Clinical Pathology).
Experienced in Teaching Pathology at various levels (PG Tutor, Senior Resident, Assistant Professor & Associate Professor) in the Department of Pathology at various Medical Colleges in Andhra Pradesh & Telangana Sates Of India.
Actively involved in Indian Association Of Pathologists & Microbiologists AP-Chapter (Ex-Treasurer).
Member : 1. Indian Association Of Pathologist & Microbiologists.
2. AP Chapter :Indian Association Of Pathologist & Microbiologists
3. European Society Of Pathology
4. United States & Canadian Academy of Pathology ( A division of IAP)
Served the Indian Army as Medical Officer In the Army Medical Corps- Short Service Commission. Rank - Major.
Won awards for PG Best Poster & Best Paper at combined state level IAPM conferences
Magdy El-Salhy is Professor of Gastroenterology and Hepatology at Bergen University, and consultant gastroenterologist at Stord Hospital, Norway. He is a member of the Editorial Boards of 9 international journals. Furthermore, he is on the referee list of a large number of international journals. He has evaluated grant applications for national and international research foundations. El-Salhy has also attended and contributed to several national and international meetings as invited speaker, or chairman. He authored 254 publications, which include original articles, invited reviews, book chapters, and books. His work has been cited in 6391 scientific articles. His research field for the last 40 years has been the neuroendocrine system of the gut, from basic science to clinical applications.
Half Covered and Half Uncovered Versus Fully Covered and Uncovered Metal Stents for Biliary Drainage in Malignant Biliary Obstruction
associate professor of Gastroenterology and Hepatology-National Liver Institute, Menoufia University-Egypt
Background and aim: given most patients with distal malignant biliary obstruction (DMBO) present in non-resectable stage and palliative endoscopic biliary drainage with fully covered (FCMS) or uncovered (UCMS) metal stent is the only available measure to improve patients’ quality of life. Half uncovered and Half covered metal stent (HCMS) has been recently introduced commercially. The adverse effects and stent functioning between FCMS and UCMS have been extensively discussed. However, the adverse effects of HCMS were not discussed.
Methods: We studied 210 patients and divided them into three groups, each group included 70 patients, HCMS, FCMS and UCMS were endoscopically inserted to achieve biliary drainage after randomization.
Results: Stent occlusion occurred in 36 patients out of 210 patients (18.6%, 17.1% and 15.7% in HCMS, FCMS and UCMS respectively), p=0.9). Stent migration occurred only in patients with FCMS in 8.6% of patients). Cholecystitis was observed in 4 patients with FCMS. Cholangitis occurred in 5.7% of patients in FCMS group. Tumor ingrowth occurred only in 10 cases among patients with UCMS (six cases associated with cholangitis) after a median of 140 days (range 52-541 days). Tumor overgrowth occurred in 4 and 5 patients with HCMS and FCMS respectively, sludge and stent occlusion occurred in 9, 7, one patients in HCMS, CMS and UCMS respectively, p value (0.04).
Conclusions: given decreased rate of migration, cholecystitis, and tumor ingrowth, the use of HCMS is preferred than the use of UCMS and FCMS in palliation for distal malignant biliary obstruction.
Introduction. More than two thirds of patients with Crohn’s disease (CD) will face one or more
surgeries during the course of life. Stenosis is a frequent complication, occurring in one third of
patients, and obstruction is the most common indication for surgery. Stricturing and penetrating
disease often coexist in the same patient.
Aim and Methods: The purpose of this review is to focus the surgical approach in the management of stricturing CD. The Authors have conducted a review of the literature of the last two decades and have revised critically their own experience.
Results and Discussion. Evaluation of patients with suspect of stenosis can be performed by
endoscopy and imaging techniques, such as ultrasonography (US), CT-enterography (CTE) or MRenterography (MRE). Patients with CD-strictures who are not responders to conservative therapy and show signs of vascular suffering or perforation risk should be operated urgently. Elective surgery is indicated in patients with persistent obstruction, despite medical therapy, especially if it is a long-lasting stenosis with a major fibrotic component. Also, in cases of stenosis without signs of flogosis, early surgery is a valid alternative to medical therapy. In all patients it is important to evaluate the ongoing therapy, considering that steroids increase the risk of postoperative complications, also the biologicals lead to an increase in complications. Endoscopic balloon dilation (EBD) is indicated in stenosis of large intestine, in stenosis of ileo-colonic anastomosis and ileum also, when they can be reached by the colonscopy/enteroscopy. Surgery (resection or strictureplasty, open or laparoscopic surgery) is based on a variety of factors, including the number, length and location of the strictures, the length of residual intestine, the presence or absence of complications (perforation, abscesses), the experience of the surgeon and, not least, the patient's preference. The intervention of choice is still resection. Concomitant abscess recommend TC guided drainage or surgical drainage. A wide stapled side-to-side anastomosis (SSSA) would be the best, as it would have lower complication rates, compared to the conventional handsewen end-to-end anastomosis (HEEA). The strictureplasty (Mikuliks, Finney, Michelassi, Taschieri, Fazio, Poggioli and other variants) are reserved for selected cases with stenosis, especially of the small bowel.
Conclusions: The management of patients with stricturing CD requires a multidisciplinary
approach. Optimization of preoperative medical treatment can reduce the incidence of
complications and probably of recurrence of the disease, and represents, therefore, the first step in the management of strictures in CD patients. Stenosis treatment may require medical theray, EBD, strictureplasty or intestinal resection. The choice between EBD, strictureplasty or resection, either laparoscopic or open surgery, is based upon the occurrence of complications of the disease, the residual intestinal length and upon the location, number and length of each stenosis.