Prof. Lallan Mishra, a senior Professor of Chemistry BHU, Varanasi, is an outstanding chemist with seminal contributions in the development of metal complexes as possible anti-cancer drugs and molecular electronic materials. Prof. Mishra has contributed significantly in the synthesis of Ru(II) and Ru(III) polypyridyl complexes and screened several of them for their anti-HIV and cytotoxic activities and discovered some of them possessing substantially higher anti-HIV activity compared to the standard azidothymidine (AZT) [Bio-org. Med. Chem., 9, 1667, 2001]. Some of the compounds synthesized by Prof. Mishra also showed cytotoxic and anti-HIV activity against ovarian carcinoma and lung-adeno carcinoma and they have been listed in WHO collections. Another class of compounds synthesized by Prof. Mishra showed cytotoxicity specially against ileocecal carcinoma and found to be many fold potent as compared to AZT (Metal-Based Drugs, 8, 65, 2001 &8, 113, 2001). Other interesting contributions from Prof. Mishra include the serendipitous observation of interaction of some of the metal complexes with calf-Thymus DNA (New J. chem. (Royal Society Journal) 24, 505, 2000) and nitrite/nitrate reductase activity. (Journal of Inorgaic BioChemistry 86, 581, 2001). Further, several of the Ru(ll) complexes synthesized by Prof. Mishra facilitated the photoinduced energy/electron transfer process. These metal complexes thus have potential as molecular electronic materials (Chemistry Letters 447, 1997, Transition Met. Chem. 25, 579, 2000 and Bull. Chem. Soc. Japan. 73, 2051, 2000). Prof. Mishra has developed new Co(III) complexes which bind to thymine and adenine bases and provided structurally interesting materials. (Bull. Mater. Sci,24, 339, 2001). More recently, Re(II) complexes have been observed to show physiological acceptability, as tested in mice and they have been found to bind to LDH. Some of the complexes showed increase in P53 level and induced release of cytochrome c and DNA cleavage. Prof. Mishra also developed simple nano-size sheet-like and tubular materials and metallo supramolecules, which have potential to act as a receptor for binding of phenol and hexa fluorobenzene. Prof. Mishra synthesized several metal polypyridyl complexes as chemical nuclease with potential cytotoxicity against several cancer cell lines both in vivo and in vitro. In this context, several copper(II) complexes of different geometry have been synthesized and characterized. The interaction of complexes with DNA were monitored using absorption and emission titrations and circular dichroism spectroscopy. These complexes were found active against Dalton's lymphoma cell lines at nano-molar concentrations (Journal of Inorganic Biochemistry, 2011). Additionally, a Pt(ll) copmplex bearing the skeleton of a simple Schiff base showed strong cytotoxicity against Hella cell line. It also binds and cleaves DNA readily in aqueous medium containing minimum amount of DMSO. Cell imaging studies using HeLa cell line carried out in the presence of complex has been considered one of the first examples of Pt complexes applied as fluorophores in cell imaging (Med. Chem. Com., 2011, 2, 1208-1216). Prof Mishra designed new metallo receptors and targeted them to selective binding with cations and anions of biological and environmental relevance. He synthesized a simple barbiturate derivative for sensing of neutral molecule. It was found to bind selectively to urea molecules in a micromolar concentration range. Theoretical studies carried out in gas phase, aqueous, and DMSO media supported this observation. (J. Physical Chemistry A, 2010). Further, Prof. Mishra’s recent findings on sensing of Cu2+, Hg2+, F- and I- has been considered of great interest (Tetrahedron Letters 54, 2013, 7151–7155, Ind. Eng. Chem. Res. 2013, 52, 15007−15014, Rsc. Adv. 2014, 4, 24038, Rsc. Adv. 2015, 5, 14382). Prof. Mishra has been regularly invited to deliver lectures at various International Conferences. To name a few: International Conference on Bioinorganic Chemistry, held in Wuhan China, April 23, 1990; Gordon Research Conference, New England College USA, 1999 on Supramolecules; World second conference on Magic Bullets, to commemorate 100th Noble Prize anniversary of Paul Ehrlich, Nuremberg Germany, Oct 2-5, 2008; International Conference on Pure and Applied Chemistry (ICPAC-2010) at University of Mauritius held during July 25-30, 2010; 12th International Conference of International Academy of Physical Sciences, P.2 I006, Dec 22-24, 2010, Jaipur India; International Conference On Coordination And Bioinorganic Chemistry, Slovakia, during June 5 – 10, 2011; Institute of Industrial Science, Tokyo University, Tokyo during Oct 11-18, 2012. He visited Japan , Germany, USA, Belgium, China, Taiwan, and Spain as visting professor and delivered series of lectures specially on meta-based drug development and on molecular recognition. Besides, within the country he delivered several lectures during various seminars and symposia and chaired the sessions.Prof Lallan Mishra served on several National Committees. To name a few: He was a Member of Evaluation Committee of UGC, New Delhi for academic Programmes; Chairman, Seminar Symposia and academic promotion Committee Faculty of Science; Member of Selection Committee at various Universities; Reviewer of various National and International Journals (Polyhedron, Royal society journal, j of molecualr structure and Indian J of Chemistry section A); Convener, National Level Symposium on Supramolecules (2006); Expert Member of Board of Studies in Several Universities of the Country; Council Member of Indian Chemical Society, Kolkata (2004-2006); Vice-President and EC member, Indian Biophysical Society (212-2016); Member of School board, NEHU, Shilong and Central University, Mizorum. He was Sectional President in Indian Council of Chemists held in KC College, Mumbai during 2004. He was a Member of Central Monitoring Committee, Central Drug Research Institute, Lucknow, India. Prof. Lalan Mishra has been bestowed with several awards in recognition of his academic achievements, which include the following: Prof. Priyadaranjan Ray, Memorial Lecture award 1997 (Indian Chemical Society); CHEMITO Award-2001 (Chemito Pvt. Ltd. Mumbai), given for best contribution in Life Sciences having Potential applications; IIS, Lecture Award, Institute of Industrial Science, Univ. Of Tokyo, Japan, July, 2005; J .C.Ghosh Memorial Lecture Award, 2007 (Indian Chemical Society); Chemical Research Society of India (CRSI), Bangalore, Bronze Medal Award 2009; Fellow, International Academy of Physical Sciences, Allahabad, 2011; IIS, Lecture Award, Institute of Industrial Science, Univ. Of Tokyo, Japan, Oct 11-18, 2012. Prof. Mishra imparted academic trainning to twenty-three Ph.D. students and five post-doctoral fellows. Besides, he has been guiding summer students.Professor Mishra has co-authored six book Chapters.