Dr. Marcela Krecmerova has completed her PhD. thesis from the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences and postdoctoral studies from the university of osnabruck, Germany. Most of her scientific career she has been working in the field of nucleoside and nucleotide analogs, many years in a close collaboration with Professor Antonin Holy. Her research is currently focused to the development of prodrugs of various biologically active molecules to improve their pharmacokinetic profile and enable their investigation as clinical drug candidates. She holds two patents and has published more than sixty original scientific papers.